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Japanese researchers from Keio University School of Medicine
in Tokyo and colleagues from the National
Institute for Child Health and Development in Tokyo,
Tokyo Women’s Medical University, and Kanazawa University
showed that cells from menstrual blood may be helpful in repairing damaged
heart tissue.
Nine women volunteered to donate menstrual blood from which the
researchers harvested the precursor cells, called mesenchymal cells (MMCs) and
cultivated them for a month, putting them together with heart cells from rats. About
20 percent of these cells began beating spontaneously and eventually formed
sheets of heart muscle tissue.
The success rate is 100 times higher than the 0.2 to 0.3 percent for stem
cells taken from human bone marrow, researcher Shunichiro Miyoshi, a cardiologist
at Keio University's school of medicine, told French news agency AFP.
“There may be a system in the near future that allows women
to use it for their own treatment,” Miyoshi said.
He further added that the cells can be stored for a long
time in a tube the size of a finger and cultivated when necessary.
"In proper storage, we would be able to stock up a tremendous count of
cells in a small space. If they are not used for 100 years, they could stay
there for 200 years or 300 years" waiting for a perfect match, he said.
According to the study, rats who had suffered heart attacks improved after
they received the menstrual blood cells. However, Miyoshi was “not entirely
happy” with the results of the experiment.
“I guess this can't be ready for clinical use yet. There should be a
definite factor that turns the cells into a heart and we want to find it,” he
said.
The study’s findings appeared in the online edition of the U.S. journal
Stem Cell.
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