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Just days after the U.S. Centers for Disease Control and
Prevention recommended that people aged 60 and older get Merck & Co. Inc’s
vaccine Zostavax to protect them against shingles, a new study by scientists
from Texas University
Medical School
in Houston
suggests that the disease tends to run in the families.
Shingles, also known as herpes zoster, is a skin rash caused
by the same virus that causes chickenpox, namely the Varicella zoster virus. After
and individual has chickenpox, this virus lives in the nervous system and is
never fully cleared from the body. Under certain circumstances, such as
emotional stress, immune deficiency, or cancer, the virus reactivates causing
shingles.
Anyone
who has ever had chickenpox is at risk for shingles, although it occurs most
commonly in people over the age of 60.
It
has been estimated that up to 1,000,000 cases of shingles occur each year in
the U.S.
and half of those occur in people 60 and older. More than 43 million adults
over the age of 60 in the U.S.
are estimated to be at risk for shingles.
For
the new study, Dr. Lindsey D. Hicks, B.S. and colleagues compared 504 patients
treated for shingles between 1992 and 2005 to 523 control individuals with other
minor or chronic skin conditions treated at the same clinic. The participants provided
personal and family history of shingles.
The
researchers found that those with shingles were about four times as likely as
the others to have had a close family member with the disease. Overall, 39.3
percent of the shingles patients had such a relative, compared to 10.5 percent
of the other patients.
“Or
study suggests a strong association between the development of herpes zoster
and having a blood relative with a history of zoster,” the study concluded.
Therefore,
these people “have a greater need for vaccination,” as they have an increased
risk of developing shingles, which pretty much explains the CDC last week
recommendation. Zostavax was found to cut the occurrence of shingles by 50
percent in people age 60 and older. The CDC said that for people ages 60 to 69,
it cuts the occurrence of the disease by 64 percent.
The
study, called “Family History as a Risk Factor for Herpes Zoster: A
Case-Control Study,” was published in the May issue of Archives of Dermatology,
a JAMA publication.
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