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People facing digestive troubles while traveling can now
breathe relieved, as results of a clinical trial showed that an experimental
vaccine patch developed by Iomai Corp. managed to keep traveler’s diarrhea
away.
The vaccine protects against Escherichia coli bacteria,
especially a strain known as Enterotoxigenic E. coli or ETEC.
For the study, 170 adults traveling to areas known to be hot
spots of tummy trouble in Guatemala
and Mexico
were given the experimental patch, which proved to be very efficient. More exactly,
during and after travel, 15 percent of the patients who got the patch developed
diarrhea of any type and just 5 percent had ETEC-related diarrhea. This
compared to 22 percent of travelers who got placebo, 10 percent of whom had
ETEC diarrhea.
Only 2 percent of those who used the patch experienced serious bouts of
illness, compared to 11 percent who did not use the patch.
Dr. Herbert DuPont of the University
of Texas in Houston who helped test the vaccine said it
prevented more than 70 percent “of the episodes of moderate or severe traveler’s
diarrhea. This vaccine is among the best we have for these kinds of diseases.”
Travelers’ diarrhea is most commonly picked up from bacteria
in Africa, Asia and Latin America, affecting up
to 27 million travelers yearly. Its symptoms include severe diarrhea, abdominal
cramps and dehydration.
The study findings were published in the Lancet.
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