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During the 50th
annual meeting of the American Society for Therapeutic Radiology and Oncology
that was held Sunday in Boston, study results showing that nodal radiation of
both axillary and supraclavicular lymph nodes is not necessary in women with pathologically
node-negative breast tumors
that have been previously surgically removed were presented by researchers.
Dr. Penny Anderson, attending physician in the radiation oncology
department at Fox Chase Cancer Center, Boston, along with her fellow
colleagues, looked at 64 women with node-negative breast cancer who had
undergone a mastectomy, monitoring them for a period of 78 months. The patients had received
radiation treatment follwing the extirpation of a larger
than five centimeters breast tumour. Of the women, 53 had radiation therapy
only to the chest wall, while the other eleven women underwent, in addition, regional lymph nodes radiation treatment.
After evaluation, doctors found that the reoccurence rate for lymph nodes in
patients who had not received the additional radiation therapy was very low,
only one of the 53 women developing a recurrence in an axillary lymph node.
Dr. Penny Anderson stated that, at the moment, radiation
treatment following a mastectomy that has removed a 5 or more centimeters large
tumor is recommended by most oncologists, although there has not been
any cogent evidence that this might improve survival. Moreover, regional node
radiotherapy could give rise to pulmonary toxicity and lymphedema, which is
also known as lymphatic obstruction, a
condition of localized fluid retention that can easily evolve into an infection
in the affected limb if it is not treated in due time.
The study’s findings
come shortly after Canadian researchers revealed that shorter radiation
time of about three weeks following a lumpectomy,
which is a non-invasive, breast-preserving procedure that involves surgically
removing a tumor in a patient’s breast, is as effective as the standard five to
seven weeks of chemotherapy.
Breast cancer
is the second most common type of cancer worldwide after lung cancer,
accounting for 10.4% of all cancer incidence. It can affect men and
women alike , since both the male and the female breasts are composed of the
same tissue. Nevertheless, breast cancer in men is approximately 100 times less
common than in women, but the survival rates are the same for both genders.
Currently, radiation therapy is standard treatment for women
who have undergone either a lumpectomy or a mastectomy. The latter procedure
involves removing one or both breast of the patient. The treatment uses high-energy
X-rays or gamma rays aimed at killing cancer cells that might remain after the
surgical procedure or that could reoccur on the post-surgery tumor site. The
treatment is generally given over a period of five to seven weeks, five days a
week. Each session lasts about 15 minutes.
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