 |
|
|
A medical breakthrough is about to happen, as chemists
announced the advanced work on the development of a fully-synthetic version of
the blood thinner known as heparin. Up until now, it was only made out of pig
intestines at there were several concerns from the U.S. Food and Drug
Administration about the dangers of contaminated batches.
Apparently, due to a contaminated batch, the animal-based
product was linked last year to at least 80 deaths and many more allergic
reactions. The new product would put some of those worries behind, offering a much
safer option.
"With the problems associated with contaminated heparin
produced from pig tissues in China, a non-animal source of this essential drug
is gaining importance," says study co-author Robert J. Linhardt, Ph.D., a
chemist with Rensselaer Polytechnic Institute in Troy, New York. "A safer
version of the drug could result in less adverse effects and fewer
deaths."
Heparin is used by doctors worldwide to prevent potentially
fatal blood clots during kidney dialysis and heart surgery. The problem with
its fabrication process, which is mostly done in China (about 70 percent), is that
when it comes to hygiene and regulatory control standards, the workshops
handling the operations are far from the environment needed by such a delicate
activity.
"If heparin is prepared the right way, it should be
consistent and safe, even from an animal source," explained Linhardt.
The new procedure, called chemoenzymatic synthesis, managed
so far to produce only small quantities of heparin and the research continues
in order to find the way of producing it on a bigger scale, which will surely
be widely adopted.
© 2007 - 2009 - eFluxMedia